Common painkillers appear to slow healing from musculoskeletal injury, warn scientists.
A new study examined the effects of the non-steroidal anti-inflammatory drugs (NSAIDs) celecoxib (Celebrex®) and indomethacin on healing.
As part of the experiment, Yale researchers made rotator cuff repairs in 180 rats. For the next 14 days, 60 of the rats were given celecoxib, 60 were given indomethacin and 60 received neither drug.
Findings showed that “traditional and cyclooxygenase-2–specific nonsteroidal anti-inflammatory drugs significantly inhibited tendon-to-bone healing.”
The study concludes that “if the results of this study are verified in a larger animal model, the common practice of administering non-steroidal anti-inflammatory drugs after rotator cuff repair should be reconsidered.”
Source: American Journal of Sports Medicine – March 2006;34:362-9.