Exciting new research shows that chiropractic adjustments may trigger blood chemical changes associated with healing.

As part of the experiment, investigators focused on two blood chemical indicators (lipid peroxidation and catalase activity). Lipid peroxidation is the process of free radicals oxidizing lipids, leading to cellular damage. Catalase is an enzyme that neutralizes the cell-damaging free radical hydrogen peroxide.

The study included 22 men with neck pain. The study participants received 6 sessions of high-velocity, low-amplitude (HVLA) manipulation 3 times a week for 2 weeks. According to the study, “blood samples were drawn from the cubital vein before treatment in the first session and after the third and sixth sessions. Neck pain improvement was assessed using a visual analog scale and the Neck Disability Index questionnaire.

“Results showed no change in lipid peroxidation. Nevertheless, the catalase activity was increased by HVLA manipulation. The same treatment reduced pain perception and disability in these subjects.”

“The results support the beneficial role of HVLA in the treatment of patients with neck pain,” conclude the study’s authors.


JMPT – May 2010;33:300-307.

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